Sasami is a key character in the Tenchi Muyo! metaseries as well as the protagonist of her own various non-canonical spinoffs.

In the Tenchi continuities, Sasami is the younger sister of Ayeka and so is also a princess of the planet Jurai. Within the Masaki extended family, Sasami usually takes on the dual role of younger sister/mother. She may be the most responsible of the group and takes care of all the cooking duties.

Sasami has appeared in every Tenchi Muyo! series, as well as/including several spinoffs based around her as the central protagonist. In almost every incarnation her personality, background, primary outfits, relationships, and abilities change. In some incarnations, her art style is altered more than others, though her basic coloring and structure remaining the same.

In the Pretty Sammy series Sasami is called Sasami Kawai, an ordinary japanese girl who receives magical powers by Tsunami and transform into the magical girl Pretty Sammy.