Here is the yearly anime DVD and Blu-ray rankings for 2010. (Dec 20 2009 - Dec 12 2010)

DVD
*1, 373,820 Evangelion: 2.22 You Can (Not) Advance
*2, 168,555 One Piece: Strong World Limited Edition
*3, 162,050 (Up)
*4, 127,832 Summer Wars
*5, 107,672 (Toy Story Special Edition)
*6, *93,859 (Toy Story 2 Special Edition)
*7, *81,380 One Piece: Strong World Standard Edition
*8, *79,384 My Neighbor Totoro (2001)

Blu-ray
*1, 449,675 Evangelion: 2.22 You Can (Not) Advance
*2, 151,832 (Toy Story 3 DVD + Blu-ray set)
*3, 105,742 Mobile Suit Gundam Unicorn vol.1
*4, 101,113 (Toy Story 3 Blu-ray + DVD set)
*5, *98,994 Mobile Suit Gundam Unicorn vol.2
*6, *83,083 One Piece: Strong World Limited Edition
*7, *79,390 Summer Wars
*8, *68,599 Evangelion: 1.11 You Are (Not) Alone (2009)
*9, *67,286 Mahou Shoujo Lyrical Nanoha The Movie 1st Limited Edition
10, *57,909 Bakemonogatari vol.4 Nadeko Snake Limited Edition
11, *55,978 Bakemonogatari vol.6 Tsubasa Cat Limited Edition
12, *53,844 Bakemonogatari vol.5 Tsubasa Cat Limited Edition
13, *52,217 Fate/stay night: Unlimited Blade Works Limited Edition
14, *38,452 K-ON!! vol.1 Limited Edition
15, *37,440 K-ON! vol.7
16, *37,166 (Up)
17, *36,059 Tales of Vesperia: The First Strike
18, *35,456 K-ON!! vol.2 Limited Edition

Source: Youtaiju